The investigation into the death of “Friends” star Matthew Perry has unveiled a shocking truth – he fell victim to a ketamine overdose in October. Prosecutors have now indicted five people, including two doctors and a street dealer, for their involvement in Perry’s tragic demise.

But what exactly is ketamine?

Ketamine is a potent anesthetic primarily used during surgeries. It can be administered via injection or IV and is closely related to the recreational drug PCP. Despite its medical applications, ketamine is also known for its euphoric effects and hallucinogenic properties, affecting the heart and breathing of the user.

Matthew Perry turned to ketamine as a treatment for depression. While not officially sanctioned for this purpose, ketamine has gained popularity in recent years for managing mental health conditions such as depression, anxiety, and pain. Perry resorted to illicit ketamine sources when his doctors refused additional doses, ultimately leading to his tragic end.

The misuse of ketamine is not limited to celebrities like Perry. Paramedics have used ketamine as a sedative in conjunction with law enforcement, with some states reevaluating this practice due to its risks. The death of Elijah McClain in 2019 shed light on the dangers of ketamine misuse, prompting a reexamination of its use in law enforcement contexts.

The dark side of ketamine is a stark reminder of the risks associated with its misuse. While the drug holds promise for certain medical conditions, its off-label use and availability through illicit channels pose significant dangers to individuals like Matthew Perry.

The Associated Press Health and Science Department is supported by the Howard Hughes Medical Institute’s Science and Educational Media Group. The AP retains full responsibility for all content.